Atheroprotective vaccination with MHC-II-restricted ApoB peptides induces peritoneal IL-10-producing CD4 T cells.

Title:

Atheroprotective vaccination with MHC-II-restricted ApoB peptides induces peritoneal IL-10-producing CD4 T cells.

identifier:	3137795
description:	epitope description:FGKQGFFPDSVNKALY antigen name:Apolipoprotein B-100 host organism:Mus musculus Apolipoprotein E null mhc allele name:H2-IAb
aggregation:	instance of dataset
availability:	available
primaryPublications:	28087520

type:	Literature
publicationVenue:	Am J Physiol Heart Circ Physiol
dates:	2017

study type:	t cell assays
subject species:	Mus musculus

fullName:	Takayuki Kimura Kevin Tse Sara McArdle Teresa Gerhardt Jacqueline Miller Zbigniew Mikulski John Sidney Alessandro Sette Dennis Wolf Klaus Ley

method:	ICS

name:	Atheroprotective vaccination with MHC-II-restricted ApoB peptides induces peritoneal IL-10-producing CD4 T cells.
description:	Cells from mice immunized with the epitope had increased IL-10 response as measured by ICS and microarray. Epitope specific cells were CCR5+ and Nur77+.

name:	iedb
homePage:	http://www.iedb.org

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