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Title: Atheroprotective vaccination with MHC-II-restricted ApoB peptides induces peritoneal IL-10-producing CD4 T cells.
identifier: 3137798
description:
epitope description:TLYALSHAVNSYFDVD
antigen name:Apolipoprotein B-100
host organism:Mus musculus Apolipoprotein E null
mhc allele name:H2-IAb
aggregation:
instance of dataset
availability:
available
primaryPublications: 28087520
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1031423
landingPage: http://www.iedb.org/assay/3137798
type:
Literature
publicationVenue:
Am J Physiol Heart Circ Physiol
dates:
2017
study type: t cell assays
subject species: Mus musculus
fullName:
Takayuki Kimura
Kevin Tse
Sara McArdle
Teresa Gerhardt
Jacqueline Miller
Zbigniew Mikulski
John Sidney
Alessandro Sette
Dennis Wolf
Klaus Ley
method:
in vivo assay
name:
Atheroprotective vaccination with MHC-II-restricted ApoB peptides induces peritoneal IL-10-producing CD4 T cells.
description:
Mice immunized with the epitope had reduced aortic atherosclerosis (lesion area) but no differences in body weight, LDL, cholesterol, or triglycerides, compared to adjuvant immunized mice.

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