Identification and characterization of enhancer agonist human cytotoxic T-cell epitopes of the human papillomavirus type 16 (HPV16) E6/E7.

Title:

Identification and characterization of enhancer agonist human cytotoxic T-cell epitopes of the human papillomavirus type 16 (HPV16) E6/E7.

identifier:	3193740
description:	epitope description:KISEYRHYC antigen name:Protein E6 host organism:Homo sapiens mhc allele name:HLA-A*02:01
aggregation:	instance of dataset
availability:	available
primaryPublications:	28389098

study type:	t cell assays
subject species:	Human papillomavirus type 16

fullName:	Kwong Y Tsang Massimo Fantini Romaine I Fernando Claudia Palena Justin M David James W Hodge Elizabeth S Gabitzsch Frank R Jones Jeffrey Schlom

method:	51 chromium

name:	Identification and characterization of enhancer agonist human cytotoxic T-cell epitopes of the human papillomavirus type 16 (HPV16) E6/E7.
description:	HLA-A2-restricted epitope-specific CTLs were shown to lyse HPVE6/E7+ CaSki cervical carcinoma cells. Agonist peptides lysed both carcinoma cell lines to a greater extent than the T cell lines generated with the native peptides.

name:	iedb
homePage:	http://www.iedb.org

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