Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus-Derived CD8+ T Cell Epitopes and Host MHC.

Title:

Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus-Derived CD8+ T Cell Epitopes and Host MHC.

Dataset

identifier:	3202265
description:	epitope description:YYSIAPHSI host organism:Mus musculus BALB/c mhc allele name:H2-Kd
aggregation:	instance of dataset
availability:	available
primaryPublications:	27903740

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1031127
landingPage:	http://www.iedb.org/assay/3202265

Publication

type:	Literature
publicationVenue:	J Immunol
dates:	2017

Dimension

study type:	t cell assays
subject species:

Person

fullName:	William J Liu Jiaming Lan Kefang Liu Yao Deng Yanfeng Yao Shaolian Wu Hong Chen Lingling Bao Haifeng Zhang Min Zhao Qihui Wang Lingxia Han Yan Chai Jianxun Qi Jincun Zhao Songdong Meng Chuan Qin George F Gao Wenjie Tan

Data Type

method:	in vivo assay

Study

name:	Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus-Derived CD8+ T Cell Epitopes and Host MHC.
description:	Mice immunized with the epitope were not protected from challenge with MERS-CoV compared with the control group. There was not improved body weight recovery after challenge or lower virus titers in the epitope-immunized group.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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