Cancer immunotherapy. A dendritic cell vaccine increases the breadth and diversity of melanoma neoantigen-specific T cells.

Title:

Cancer immunotherapy. A dendritic cell vaccine increases the breadth and diversity of melanoma neoantigen-specific T cells.

identifier:	3241729
description:	epitope description:IILVAVPHV host organism:Homo sapiens mhc allele name:HLA-A*02:01
aggregation:	instance of dataset
availability:	available
primaryPublications:	25837513

study type:	t cell assays
subject species:

fullName:	Beatriz M Carreno Vincent Magrini Michelle Becker-Hapak Saghar Kaabinejadian Jasreet Hundal Allegra A Petti Amy Ly Wen-Rong Lie William H Hildebrand Elaine R Mardis Gerald P Linette

method:	51 chromium

name:	Cancer immunotherapy. A dendritic cell vaccine increases the breadth and diversity of melanoma neoantigen-specific T cells.
description:	Vaccine-induced neo-epitope-specific cytolysis was measured. Cytotoxic activity was also observed upon co-culture with DM6 cells expressing AAS-tandem minigene constructs (TMCs) which enable evaluation of neo-antigen processing and presentation.

name:	iedb
homePage:	http://www.iedb.org

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