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Title: Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition.
identifier: 3364223
description:
epitope description:EENLLDFVRF
antigen name:Epstein-Barr nuclear antigen 6
host organism:Homo sapiens
t cell receptor:DM1
mhc allele name:HLA-B*44:02
aggregation:
instance of dataset
availability:
available
primaryPublications: 19139173
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1013516
landingPage: http://www.iedb.org/assay/3364223
type:
Literature
publicationVenue:
J Exp Med
dates:
2009
study type: t cell assays
subject species: Human gammaherpesvirus 4
fullName:
Julia K Archbold
Whitney A Macdonald
Stephanie Gras
Lauren K Ely
John J Miles
Melissa J Bell
Rebekah M Brennan
Travis Beddoe
Matthew C J Wilce
Craig S Clements
Anthony W Purcell
James McCluskey
Scott R Burrows
Jamie Rossjohn
method:
binding assay
name:
Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition.
description:
The DM1 TCR bound to the HLA-B*4402/epitope complex with an affinity that was >10-fold less compared to binding the HLA-B*4405/epitope complex (300 nM).

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