Involvement of both T cell receptor V alpha and V beta variable region domains and alpha chain junctional region in viral antigen recognition.

Title:

Involvement of both T cell receptor V alpha and V beta variable region domains and alpha chain junctional region in viral antigen recognition.

identifier:	3466157
description:	epitope description:IKAVYNFATCG antigen name:Pre-glycoprotein polyprotein GP complex host organism:Mus musculus P14 TCR Tg t cell receptor:P14 mhc allele name:H2-Db
aggregation:	instance of dataset
availability:	available
primaryPublications:	1716213

study type:	t cell assays
subject species:	Lymphocytic choriomeningitis mammarenavirus

fullName:	D Brä ndle K Bü rki V A Wallace U H Rohrer T W Mak B Malissen H Hengartner H Pircher

method:	51 chromium

name:	Involvement of both T cell receptor V alpha and V beta variable region domains and alpha chain junctional region in viral antigen recognition.
description:	Epitope-specific spleen cells lysed MC57G target cells infected with LCMV-WE. LCMV-WE variant 8.7-infected cells were not lysed by the epitope-specific clone. This in vivo selected virus variant differs from LCMV-WE in one amino acid (substitution Val35 to Leu35) in the gp aa 32-42 epitope.

name:	iedb
homePage:	http://www.iedb.org

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