Identification of a crucial energetic footprint on the alpha1 helix of human histocompatibility leukocyte antigen (HLA)-A2 that provides functional interactions for recognition by tax peptide/HLA-A2-specific T cell receptors.

Title:

Dataset

identifier:	3465634
description:	epitope description:LLFGYPVYV antigen name:Protein Tax-1 host organism:Homo sapiens t cell receptor:A6 mhc allele name:HLA-A*02:01 W167A mutant
aggregation:	instance of dataset
availability:	available
primaryPublications:	11238586

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1008073
landingPage:	http://www.iedb.org/assay/3465634

Publication

type:	Literature
publicationVenue:	J Exp Med
dates:	2001

Dimension

study type:	t cell assays
subject species:	Human T-lymphotropic virus 1

Person

fullName:	B M Baker R V Turner S J Gagnon D C Wiley W E Biddison

Data Type

method:	binding assay

Study

name:	Identification of a crucial energetic footprint on the alpha1 helix of human histocompatibility leukocyte antigen (HLA)-A2 that provides functional interactions for recognition by tax peptide/HLA-A2-specific T cell receptors.
description:	Off rate was measured by Surface Plasmon Resonance for binding of A6 TCR to W167A mutant HLA-0201 loaded with the epitope.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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