Characterization of CD4 T Cell Epitopes of Infliximab and Rituximab Identified from Healthy Donors.

Title:

Characterization of CD4 T Cell Epitopes of Infliximab and Rituximab Identified from Healthy Donors.

identifier:	3243350
description:	epitope description:QVQLQQPGAELVKPG antigen name:Immunoglobulin host organism:Homo sapiens mhc allele name:HLA class II
aggregation:	instance of dataset
availability:	available
primaryPublications:	28529511

study type:	t cell assays
subject species:	Mus musculus

fullName:	Moustafa Hamze Sylvain Meunier Anette Karle Abdelaziz Gdoura Amé lie Goudet Natacha Szely Marc Pallardy Franck Carbonnel Sebastian Spindeldreher Xavier Mariette Corinne Miceli-Richard Bernard Maillè re

method:	ELISPOT

name:	Characterization of CD4 T Cell Epitopes of Infliximab and Rituximab Identified from Healthy Donors.
description:	The epitope is derived from a mouse/human chimeric monoclonal antibody. Rituximab-specific CD4+ T cell lines from healthy donors were tested for reactivity to the epitope. Infliximab is a chimeric (mouse-human) monoclonal antibody used therapeutically as an anti-TNFalpha anti-inflammatory treatment.

name:	iedb
homePage:	http://www.iedb.org

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