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Title: Therapeutic protein deimmunization by T-cell epitope removal: antigen-specific immune responses in vitro and in vivo.
identifier: 3258582
description:
epitope description:V21
antigen name:Hirudin-PA
host organism:Homo sapiens
aggregation:
instance of dataset
availability:
available
primaryPublications: 28418077
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1031686
landingPage: http://www.iedb.org/assay/3258582
type:
Literature
publicationVenue:
APMIS
dates:
2017
study type: t cell assays
subject species: Hirudo medicinalis
fullName:
Saeme Asgari
Azadeh Ebrahim-Habibi
Mehdi Mahdavi
Mohammad Choopani
Hasan Mirzahoseini
method:
ELISPOT
name:
Therapeutic protein deimmunization by T-cell epitope removal: antigen-specific immune responses in vitro and in vivo.
description:
Mutation of the epitopic residue abolished the IFNg response.

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