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Title: A novel multi-epitope vaccine based on Dipeptidyl Peptidase 4 prevents streptozotocin-induced diabetes by producing anti-DPP4 antibody and immunomodulatory effect in C57BL/6J mice.
identifier: 3338766
description:
epitope description:IPALDSLTPANED
antigen name:60 kDa heat shock protein, mitochondrial (UniProt:P10809)
host organism:Mus musculus C57BL/6
aggregation:
instance of dataset
availability:
available
primaryPublications: 28376584
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1031557
landingPage: http://www.iedb.org/assay/3338766
type:
Literature
publicationVenue:
Biomed Pharmacother
dates:
2017
study type: t cell assays
subject species: Homo sapiens
fullName:
Zhixin Li
Jinzhi Fang
Rui Jiao
Xiaomin Wei
Yanjie Ma
Xiaoran Liu
Peng Cheng
Taiming Li
method:
in vivo assay
name:
A novel multi-epitope vaccine based on Dipeptidyl Peptidase 4 prevents streptozotocin-induced diabetes by producing anti-DPP4 antibody and immunomodulatory effect in C57BL/6J mice.
description:
80% of epitope immunized mice survived as compared to 60% of control animals, however, the epitope did not control hyperglycemia.

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