Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells.

Dataset

identifier:	3349833
description:	epitope description:DWVSLWKGFSF antigen name:Collagen alpha-3(IV) chain host organism:Mus musculus HLA-DR15 Tg IAbeta null mhc allele name:HLA-DRB1*15:01
aggregation:	instance of dataset
availability:	available
primaryPublications:	28467828

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1031891
landingPage:	http://www.iedb.org/assay/3349833

Publication

type:	Literature
publicationVenue:	Nature
dates:	2017

Dimension

study type:	t cell assays
subject species:	Mus musculus

Person

fullName:	Joshua D Ooi Jan Petersen Yu H Tan Megan Huynh Zoe J Willett Sri H Ramarathinam Peter J Eggenhuizen Khai L Loh Katherine A Watson Poh Y Gan Maliha A Alikhan Nadine L Dudek Andreas Handel Billy G Hudson Lars Fugger David A Power Stephen G Holt P Toby Coates Jon W Gregersen Anthony W Purcell Stephen R Holdsworth Nicole L La Gruta Hugh H Reid Jamie Rossjohn A Richard Kitching

Data Type

method:	ELISPOT

Study

name:	Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells.
description:	Human alpha3 135-145 (GWISLWKGFSF)-specific CD4+ T cells isolated from spleen and lymph nodes of epitope-immunized HLA-DR15 Tg mice responded to the recombinant mouse alpha3(IV)NC1 protein.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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