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Title: An extensive antigenic footprint underpins immunodominant TCR adaptability against a hypervariable viral determinant.
identifier: 3479579
description:
epitope description:HSKKKCDEL
antigen name:Genome polyprotein
host organism:Homo sapiens
t cell receptor:DD31
mhc allele name:HLA-B*08:01
aggregation:
instance of dataset
availability:
available
primaryPublications: 25355921
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1028368
landingPage: http://www.iedb.org/assay/3479579
type:
Literature
publicationVenue:
J Immunol
dates:
2014
study type: t cell assays
subject species: Hepatitis C virus
fullName:
Usha K Nivarthi
Stephanie Gras
Lars Kjer-Nielsen
Richard Berry
Isabelle S Lucet
John J Miles
Samantha L Tracy
Anthony W Purcell
David S Bowden
Margaret Hellard
Jamie Rossjohn
James McCluskey
Mandvi Bharadwaj
method:
binding assay
name:
An extensive antigenic footprint underpins immunodominant TCR adaptability against a hypervariable viral determinant.
description:
The affinity was determined by Surface plasmon resonance (SPR).

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