High affinity xenoreactive TCR:MHC interaction recruits CD8 in absence of binding to MHC. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

High affinity xenoreactive TCR:MHC interaction recruits CD8 in absence of binding to MHC.

Dataset

identifier:	3467322
description:	epitope description:ALWGFFPVL antigen name:ER membrane protein complex subunit 7 host organism:Mus musculus C57BL/6 t cell receptor:AHIII 12.2 mhc allele name:HLA-A*02:01
aggregation:	instance of dataset
availability:	available
primaryPublications:	12496422

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1020639
landingPage:	http://www.iedb.org/assay/3467322

Publication

type:	Literature
publicationVenue:	J Immunol
dates:	2003

Dimension

study type:	t cell assays
subject species:	Homo sapiens

Person

fullName:	Jennifer Buslepp Samantha E Kerry Doug Loftus Jeffrey A Frelinger Ettore Appella Edward J Collins

Data Type

method:	binding assay

Study

name:	High affinity xenoreactive TCR:MHC interaction recruits CD8 in absence of binding to MHC.
description:	The affinity was determined by Surface plasmon resonance (SPR).

Data Repository

name:	iedb
homePage:	http://www.iedb.org

Feedback?

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.