Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 3467573 |
| description: |
epitope description:LLGDLFGV
antigen name:E3 ubiquitin-protein ligase Mdm2 (UniProt:Q00987)
host organism:Mus musculus C57BL/6 HLA-A*0201 Tg human CD8 Tg
t cell receptor:CD8 x A2Kb 81
mhc allele name:HLA-A*02:01
|
| aggregation: |
instance of dataset
|
| availability: |
available
|
| primaryPublications: |
11577350 |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1031796 |
| landingPage: |
http://www.iedb.org/assay/3467573 |
| type: |
Literature
|
| publicationVenue: |
Nat Immunol
|
| dates: |
2001
|
| study type: | t cell assays |
| subject species: | Homo sapiens |
| fullName: |
T Stanislawski
R H Voss
C Lotz
E Sadovnikova
R A Willemsen
J Kuball
T Ruppert
R L Bolhuis
C J Melief
C Huber
H J Stauss
M Theobald
|
| method: |
51 chromium
|
| name: |
Circumventing tolerance to a human MDM2-derived tumor antigen by TCR gene transfer.
|
| description: |
The epitope specific clone lysed cell lines expressing the protein, including the human osteosarcoma line Saos-2 transfected with the MDM2 gene and LG2 EBV-LCL. A partially humanized high-affinity T cell antigen receptor (TCR) was also positive.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
