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Title: Narrowing of human influenza A virus-specific T cell receptor alpha and beta repertoires with increasing age.
identifier: 3467694
description:
epitope description:GILGFVFTL
antigen name:Matrix protein 1
host organism:Homo sapiens
mhc allele name:HLA-A*02:01
aggregation:
instance of dataset
availability:
available
primaryPublications: 25609818
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1028816
landingPage: http://www.iedb.org/assay/3467694
type:
Literature
publicationVenue:
J Virol
dates:
2015
study type: t cell assays
subject species: Influenza A virus
fullName:
Anna Gil
Maryam B Yassai
Yuri N Naumov
Liisa K Selin
method:
in vitro assay
name:
Narrowing of human influenza A virus-specific T cell receptor alpha and beta repertoires with increasing age.
description:
Proliferation was determined by counting numbers of CD8+ T cells. Epitope specific T cell responses narrowed with increasing age, as measured by Valpha and Vbeta usage and included usage of a single identical VA12-JA29 clonotype in all 8 of the older donors.

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