NY-ESO-1 TCR single edited stem and central memory T cells to treat multiple myeloma without graft-versus-host disease.

Title:

NY-ESO-1 TCR single edited stem and central memory T cells to treat multiple myeloma without graft-versus-host disease.

identifier:	3468059
description:	epitope description:SLLMWITQC antigen name:Cancer/testis antigen 1 host organism:Homo sapiens t cell receptor:IG4 mhc allele name:HLA-A*02:01
aggregation:	instance of dataset
availability:	available
primaryPublications:	28637663

study type:	t cell assays
subject species:	Homo sapiens

fullName:	Sara Mastaglio Pietro Genovese Zulma Magnani Eliana Ruggiero Elisa Landoni Barbara Camisa Giulia Schiroli Elena Provasi Angelo Lombardo Andreas Reik Nicoletta Cieri Martina Rocchi Giacomo Oliveira Giulia Escobar Monica Casucci Bernhard Gentner Antonello Spinelli Anna Mondino Attilio Bondanza Luca Vago Maurilio Ponzoni Fabio Ciceri Michael C Holmes Luigi Naldini Chiara Bonini

method:	ELISPOT

name:	NY-ESO-1 TCR single edited stem and central memory T cells to treat multiple myeloma without graft-versus-host disease.
description:	Epitope sequence was published in the cited reference Robbins et al., J Immunol. 2008 May 1;180(9):6116-31 [PMID: 18424733]. Complete edited T cells resulted in slightly more IFNg than single edited or TCR transferred cells.

name:	iedb
homePage:	http://www.iedb.org

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