Structural and kinetic basis for heightened immunogenicity of T cell vaccines. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Structural and kinetic basis for heightened immunogenicity of T cell vaccines.

Dataset

identifier:	3468275
description:	epitope description:SLLMWITQV host organism:Homo sapiens t cell receptor:1G4 mhc allele name:HLA-A*02:01
aggregation:	instance of dataset
availability:	available
primaryPublications:	15837811

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1013985
landingPage:	http://www.iedb.org/assay/3468275

Publication

type:	Literature
publicationVenue:	J Exp Med
dates:	2005

Dimension

study type:	t cell assays
subject species:

Person

fullName:	Ji-Li Chen Guillaume Stewart-Jones Giovanna Bossi Nikolai M Lissin Linda Wooldridge Ed Man Lik Choi Gerhard Held P Rod Dunbar Robert M Esnouf Malkit Sami Jonathan M Boulter Pierre Rizkallah Christoph Renner Andrew Sewell P Anton van der Merwe Bent K Jakobsen Gillian Griffiths E Yvonne Jones Vincenzo Cerundolo

Data Type

method:	binding assay

Study

name:	Structural and kinetic basis for heightened immunogenicity of T cell vaccines.
description:	The epitope is analog of the NY-ESO-1(157-165) peptide and has the mutation: C9->V9. The affinity of the 1G4 TCR for the epitope/HLA-A2 complex was determined by surface plasmon resonance.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

Feedback?

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.