The shaping of T cell receptor recognition by self-tolerance. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

The shaping of T cell receptor recognition by self-tolerance.

Dataset

identifier:	3468634
description:	epitope description:FLRGRAYGL antigen name:Epstein-Barr nuclear antigen 3 host organism:Homo sapiens t cell receptor:LC13 mhc allele name:HLA-B*08:01
aggregation:	instance of dataset
availability:	available
primaryPublications:	19167249

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1014251
landingPage:	http://www.iedb.org/assay/3468634

Publication

type:	Literature
publicationVenue:	Immunity
dates:	2009

Dimension

study type:	t cell assays
subject species:	Human gammaherpesvirus 4

Person

fullName:	Stephanie Gras Scott R Burrows Lars Kjer-Nielsen Craig S Clements Yu Chih Liu Lucy C Sullivan Melissa J Bell Andrew G Brooks Anthony W Purcell James McCluskey Jamie Rossjohn

Data Type

method:	51 chromium

Study

name:	The shaping of T cell receptor recognition by self-tolerance.
description:	The T cell clone LC13 from a HLA B8+, B44+, EBV-positive individual lysed target cells loaded with the epitope. Amino acid substitutions within the epitope at position 8 abrogated reactivity, while those at position 1 had no effect.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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