The peptide specificity of the endogenous T follicular helper cell repertoire generated after protein immunization

ID: SDY139

Description: T follicular helper (Tfh) cells potentiate high-affinity, class-switched antibody responses, the predominant correlate of protection from vaccines. De...

Immune Response to Yellow Fever Vaccination in Adults With Atopic Dermatitis

ID: SDY15

Description: The main objective of the Atopic Dermatitis and Vaccinia Network (ADVN) is to reduce the risk of eczema vaccinatum (EV) following smallpox vaccination...

Immunologic and genomic signatures of response to Hepatitis C Virus infection.

ID: SDY162

Description: Examine the immune response in primary immune cells from subjects who have spontaneously cleared HCV compared to HCV chronically infected subjects

Innate Immune Pathways in Elderly and Immunosuppressed Populations 2011

ID: SDY194

Description: Innate Immune Pathways in Elderly and Immunosuppressed Populations

Responses to Influenza Vaccination in Systemic Lupus Year 3 2007-2008

ID: SDY198

Description: Influenza is an important pathogen in the United States, with approximately 20,000 deaths per year, mainly among elderly people or those with underlyi...

Responses to Influenza Vaccination in Systemic Lupus Year 4 2008-2009

ID: SDY199

Description: Influenza is an important pathogen in the United States, with approximately 20,000 deaths per year, mainly among elderly people or those with underlyi...

Assess the association between immune response genotype set and susceptibility to neuroinvasive disease.

ID: SDY20

Description: We propose to identify polymorphic immune response genes associated with neurological complications to WNv infection. Our preliminary draft of 156 gen...

Exploration of molecular mechanism(s) for TLR ligand response differences between adults and neonates

ID: SDY283

Description: The study performed expression microarrays on RNA from purified subsets of neonatal and adult APCs, which were stimulated or not stimulated with a TLR...

Modeling Pulmonary Immunity: Evaluation of the Innate Immune Response to Pathogens 1) Francisella tularensis 2) Mycobacterium tuberculosis and 3) Infl...

ID: SDY288

Description: A greater understanding of how alveolar macrophages respond to pathogens is important for the design of novel therapeutic agents for treatment of pote...

Live Kidney Donor Study -Renal Function Study (RELIVE-06)

ID: SDY291

Description: As part of a cross-sectional study of living kidney donors from 5 to more than 50 years following donor nephrectomy, this study's goal is to accuratel...

RELIVE Informed Consent Study (RELIVE-03)

ID: SDY292

Description: The goal of this study was to study informed consent by the living donor. This study used surveys to evaluate the understanding of risk and psychologi...

Live Lung Donor Cross-sectional Cohort Study (RELIVE-05)

ID: SDY294

Description: The Live Lung Donor Cross-sectional Cohort Study (RELIVE-05) aimed to determine the effects of live lung donation on lung function, quality of life, m...

Heritable influence on the B and T cell receptor repertoire

ID: SDY675

Description: The adaptive immune systems capability to protect the body requires a highly diverse lymphocyte antigen receptor repertoire. However, the influence of...

Human Elispot Assay with peptide.

ID: SDY680

Description: Determining CD8 T cell responses to HLA-A02 restricted Influenza A epitopes

ADVN Biomarker Registry Study: CMI/Ab-Vaccinia Substudy

ID: SDY7

Description: To measure total and specific antibody titers and T cell responses in a sample of subjects who experienced eczema vaccinatum (EV) and a group of subje...

Human Aging and CMV

ID: SDY736

Description: Delineate the effect of aging from that of cytomegalovirus (CMV) infection upon relative and absolute changes in blood T cell subsets using a cohort o...

Investigating Alterations to the Nasal Microbiome after Vaccination with LAIV

ID: SDY753

Description: The goal of this proposal is to characterize alterations to the nasal microbiome after vaccination with the 2012-2013 seasonal LAIV and to correlate t...

B and T Cell Determinants of Influenza Vaccine Responses in the Elderly 2009 (see companion study SDY460)

ID: SDY773

Description: Application of high-throughput DNA sequencing of the IGH gene rearrangements to study the B cell repertoires over two successive years in 27 individua...

Causal Relationship of Maternal Height on Birth Size and Gestational Age at Birth

ID: SDY776

Description: Mendelian randomization analysis was conducted to assess the relationship between maternal height, gestational age and fetal growth measures. This stu...

Diamond-Wofsy ITN002AI: Treating Systemic Lupus Erythematosus (SLE) Patients with CTLA4-IgG4m (RG2077)

ID: SDY798

Description: SLE is a chronic, inflammatory autoimmune disorder that may affect many organ systems, including the skin, joints, and internal organs. RG2077 has bee...