HP47

ID: SDY601

Description: WT and PPARgfl/fl:LysCre+ (R2+) mice were infected with 5x10e7 CFU of different Helicobacter pylori strains (26695, SS1 and PMSS1). A control uninfect...

ADRN Influenza Vaccine Pilot (ADRN-03)

ID: SDY618

Description: This is a single center, open-label, mechanistic study designed to determine the variance of the antibody response in non-atopic and ADEH- participant...

Immunologic and genomic signatures of influenza vaccine response - 2010 (see companion studies SDY400, SDY404, SDY520)

ID: SDY63

Description: Project 1: Immunologic and genomic signatures of influenza vaccine response.

Two separate defects affecting true naive or virtual memory T cell precursors combine to reduce naive T cell responses with aging.

ID: SDY649

Description: Naive T cell responses are eroded with aging. We and others have recently shown that unimmunized old mice lose ? 70% of Ag-specific CD8 T cell precurs...

WNV induces pro-apoptotic miRNA

ID: SDY651

Description: MicroRNAs (miRNAs) are a class of noncoding small RNAs that regulate multiple cellular processes, as well as the replication and pathogenesis of many ...

Lifespan-extending caloric restriction or mTOR inhibition impair adaptive immunity of old mice by distinct mechanisms.

ID: SDY654

Description: Aging of the world population and a concomitant increase in age-related diseases and disabilities mandates the search for strategies to increase healt...

LEAP ITN032AD: Induction of Tolerance through Early Introduction of Peanut in High-Risk Children, LEAP-On ITN049AD: The Persistence of Oral Tolerance ...

ID: SDY660

Description: ITN032AD: Allergic reactions to peanuts are potentially life-threatening and, in some children, can result from ingestion of only trace quantities of ...

The immune signature of palmoplantar pustulosis

ID: SDY667

Description: This study will compare adult patients with CPP(chronic plaque type psoriasis ), who are currently not undergoing topical, systemic or biologic treatm...

Systems scale interactive exploration reveals quantitative and qualitative differences in response to 2009-2010 Fluzone influenza vaccine and pneumoco...

ID: SDY180

Description: Systems immunology approaches were employed to investigate innate and adaptive immune responses to influenza and pneumococcal vaccines. These two non-...

Immune Responses to Seasonal TIV 2010-2011 Influenza Vaccination in Humans (see companion study SDY396,SDY564)

ID: SDY224

Description: High-frequency sampling combined with systems biology analysis of human peripheral blood cells following influenza vaccination was used to investigate...

Determinants of human NK cell diversity by mass cytometry

ID: SDY232

Description: Natural Killer (NK) cells play critical roles in immune defense and reproduction, yet remain the most poorly understood lymphocyte population. Because...

Simulation and Prediction of the Adaptive Immune Response and Quantification of Early and Adaptive Immune Response Kinetics to Influenza A Virus Infec...

ID: SDY241

Description: Seasonal and pandemic influenza A virus (IAV) continues to be a public health threat. Modeling approaches were used combined with experimental data to...

T cell responses to H1N1v and a longitudinal study of seasonal influenza vaccination (TIV) - 2009 (See companion studies SDY315 2012 / SDY314 2008 / S...

ID: SDY312

Description: Systems biology approach to examine effects of seasonal flu vaccination in adults of different ages on gene expression, cytokine stimulation and serum...

T cell responses to H1N1v and a longitudinal study of seasonal influenza vaccination (TIV) - 2012 (See companion studies SDY311 2010 / SDY312 2009 / S...

ID: SDY315

Description: Systems biology approach to examine effects of seasonal flu vaccination in adults of different ages on gene expression, cytokine stimulation and serum...

Systems Biology Approach to Study Influenza Vaccine 2010-11 in Healthy Children (see companion studies SDY144, SDY368, SDY387)

ID: SDY387

Description: The treatment of pediatric immune system dysfunctions depends upon the basic understanding of its molecular and cellular components, as well as the in...

Study to measure the immune response to the influenza vaccine in patients with chronic plaque psoriasis

ID: SDY416

Description: Interleukin-12 (IL-12) and interleukin-23 are heterodimeric cytokines, with a common p40 subunit and a unique chain (IL-12p35 and IL-23p19). The p40 ...

Monozygotic and Dizygotic Twin Pair T-Cell Responses to Influenza Vaccination 2010

ID: SDY515

Description: Evaluate the variation in immune response between individuals and assess whether it changes as a function of age and similarity in genetic and environ...

Natural Killer cells in resistance to infection with West Nile virus

ID: SDY517

Description: Examine the response of primary NK cells from subjects with a history of asymptomatic or severe infection with West nile virus

Monozygotic and Dizygotic Twin Pair T-Cell Responses to Influenza Vaccination 2011

ID: SDY519

Description: Evaluate the variation in immune response between individuals and assess whether it changes as a function of age and similarity in genetic and environ...

Immunologic and genomic signatures of influenza vaccine response - 2014

ID: SDY640

Description: Project 1: Immunologic and genomic signatures of influenza vaccine response - year5 2014