Humoral and Cell-Mediated Immune Responses to Vaccinia Virus Immunization ImmuneSpace

ID: SDY28

Description: Our broad objective is to examine the role of candidate human immune response gene polymorphisms (and their receptors, expression and function) in int...

Cytometry by time-of-flight shows combinatorial cytokine expression and virus-specific cell niches within a continuum of CD8+ T cell phenotypes ImmuneSpace

ID: SDY207

Description: High dimensional analysis of CD8+ T cell phenotype and function

TIV 2008 vaccination of CD95-/- mice and ELISA for detection of influenza-specific antibodies ImmuneSpace

ID: SDY215

Description: Evaluation of the mouse immune response to influenza vaccination. ELISA was used to examine the immune response of mutant mice (MRL/Mpj-Faslpr/J (Mpj...

Systems Biology Analysis of the response to Licensed Hepatitis B Vaccine (HEPLISAV) in Whole Blood (see companion studies SDY816 and SDY690) ImmuneSpace

ID: SDY299

Description: This project will contribute to the overall vision and goals of this U19 by analyzing the role of adjuvants in the humoral response to hep B vaccinati...

T cell responses to H1N1v and a longitudinal study of seasonal influenza vaccination (TIV) - 2008 (See companion studies SDY315 2012 / SDY312 2009 / S... ImmuneSpace

ID: SDY314

Description: Systems biology approach to examine effects of seasonal flu vaccination in adults of different ages on gene expression, cytokine stimulation and serum...

Systems Biology Approach to Study Influenza Vaccine 2013-14 in Healthy Children (see companion studies SDY364, SDY144, SDY387) ImmuneSpace

ID: SDY368

Description: The treatment of pediatric immune system dysfunctions depends upon the basic understanding of its molecular and cellular components, as well as the in...

B and T Cell Determinants of Influenza Vaccine Responses in the Elderly 2008 (see companion study SDY773) ImmuneSpace

ID: SDY460

Description: Application of high-throughput DNA sequencing of the IGH gene rearrangements to study the B cell repertoires over two successive years in 27 individua...

CMV CD8 T Cells ImmuneSpace

ID: SDY1041

Description: We present human T cell responses in multiple sites including blood, lymphoid, mucosal and secretory tissues of 20 CMV seropositive donors. Overall, C...

Early-life compartmentalization of human T cells ImmuneSpace

ID: SDY1097

Description: Knowledge of human immune responses during early life remains sparse, owing to the difficulty and impracticality of obtaining blood and tissue samples...

CD4 Nicaragua Epitope ID ImmuneSpace

ID: SDY1109

Description: We performed DENV-specific epitope screening studies in the general population of Managua. Peptides with the capacity to bind HLA DR molecules most c...

Immunologic and genomic signatures of influenza vaccine response - 2010 (see companion studies SDY400, SDY404, SDY520) ImmuneSpace

ID: SDY63

Description: Project 1: Immunologic and genomic signatures of influenza vaccine response.

Systems Biology Approach to Analysis of 2010-11 TIV Fluzone Influenza Vaccine Response in Healthy Individuals (see companion studies SDY301, SDY296) ImmuneSpace

ID: SDY74

Description: This study will measure the immune response to the influenza vaccine The long-term goal is to develop improved vaccines to infectious diseases such a...

Cellular and molecular characterization of the immune response in healthy NIH employees at baseline and after immunization with the H1N1 or seasonal i... ImmuneSpace

ID: SDY80

Description: The Center for Human Immunology, Autoimmunity, and Inflammatory Diseases proposes this protocol designed to obtain blood from healthy adult subjects (...

Systems Biology Approach to Analysis of 2011-12 TIV Fluzone Influenza Vaccine Response in Healthy Individuals (see companion studies SDY74, SDY301) ImmuneSpace

ID: SDY296

Description: This project will contribute to the overall vision and goals of this U19 by analyzing the immune response to Flu vaccination in healthy individuals. T...

Systems Biology Approach to Analysis of 2012-13 TIV Fluzone Influenza Vaccine Response in Healthy Individuals (see companion studies SDY74, SDY296) ImmuneSpace

ID: SDY301

Description: This project will contribute to the overall vision and goals of this U19 by analyzing the immune response to Flu vaccination in healthy individuals. T...

Plasmablast response to inactivated and live attenuated influenza vaccines (TIV3/TIV3 ID) in 2012 ImmuneSpace

ID: SDY305

Description: To study the plasmablast response to 2012 seasonal inactivated influenza vaccine

Immunologic and genomic signatures of influenza vaccine response - 2011 (see companion studies SDY63, SDY400, SDY520) ImmuneSpace

ID: SDY404

Description: Project 1: Immunologic and genomic signatures of influenza vaccine response - year2 2011

Immune Responses to Influenza-Like Illness ImmuneSpace

ID: SDY406

Description: To investigate the nasal transcriptional response and peripheral plasmablast response in acute influenza infection

Plasmablast response to inactivated and live attenuated influenza vaccines (TIV3/TIV3 ID) in 2013 ImmuneSpace

ID: SDY472

Description: This study will be conducted with up to 40 generally healthy children

Humoral responses to West Nile virus ImmuneSpace

ID: SDY508

Description: Integrate two high-throughput technologies namely, microengraving-based screening of primary B cells and next-generation sequencing to examine the rel...